Hemp in pain – hemp seed, the Seed of Cannabis
For painful conditions (eg, joint pain, migraine, neuralgia), the positive effects of cannabis have been known for centuries. In severe pain, the dose of opiates or other painkillers can be reduced with concomitant use of cannabis.
Other effects of cannabis often have a favorable effect, such as the muscle-relaxing effect or the anti-inflammatory effect. Opiates often cause nausea, which can be combated with cannabis. Cannabis works well on deep pain, while increasing surface sensitivity. The analgesic effect of cannabis is comparable to the opiate effect.
Both act on the central nervous system and the pain pathways in the spinal cord. you
In addition, a mood change leads to a distancing from the pain, which is then no longer perceived as so dominant and threatening. Research is currently focusing on the analgesic properties of cannabinoids.
International study examines effect on rheumatism and migraine
Cannabis, better known as hemp, has been used as a drug and as a drug for about 4,000 years, mainly in India, China and Egypt. The most important ingredients of the hemp plant are the so-called cannabinoids. The plant contains about 65 different cannabinoids. They are very different in terms of usability as a pharmaceutical raw material. The best studied are the cannabinoids dronabinol and cannabidol. The use of cannabis products as pharmaceuticals is regulated by law. Since 1998, among other things, dronabinol is prescriptive by physicians in certain diseases. Now, a European research group of extracts of the cannabis plant wants to develop an effective drug for migraine and rheumatoid arthritis. The scientists have presented their project, which promotes the EU with 1.5 million euros, last week in Freiburg.
The millennia-old experience with the hemp plant as a painkiller want to revive the European researchers for two of the biggest common diseases – migraine and rheumatism. The Freiburg project manager Bernd Fiebich:
One of the first described effects of hemp in China was rheumatic diseases, and therefore one can almost assume that it has an effect, and therefore the idea is to develop a new rheumatism, and of course on a side effect poor basis, so that people can take the medication for a longer period of time without fear of having side effects.
Strong side effects have the conventional biochemistry in their limits. The so-called “cox-2-inhibitors”, including rheumatism, increase the risk of heart attack; Therefore, they may no longer be prescribed for patients with heart disease or patients with an increased risk of stroke. Unnecessary or insufficient effect of preparations is also the problem for the 52-year-old Petra Lütke, one of around 8 million migraine sufferers in Germany:
I have gotten really bad this year and tried three different cortisone medications, but none of them worked. The first one had the side effect that I had very strong tremors and tingling, the second medication did not help, and now I have a combination that works very well.
There is a great need for new, better medicines, and there is still no sign of any breakthrough in the pharmaceutical industry. The medicinal plant researchers come across this gap: A low-cost cannabis drug could replace expensive migraine supplements. However, the future cannabis pill has little to do with hashish, researcher Dr. Fiebich:
Of course, people should not get intoxicated when taking the drug. But in the end, the state of intoxication is due to smoking, and our idea is that in the past people made a tea, have made plant extracts, and we want to do it as well, that we develop a plant extract, which is then taken orally, and then in the Ultimately, relatively little, as good as not causing high-noise conditions.
Cannabis relieves pain, stimulates appetite and weakens inflammatory processes – this is what cancer patients report. Patients with multiple sclerosis and AIDS patients could also be helped with cannabis drugs. Isolated evidence that is not supported by controlled clinical trials. The researchers are challenged:
So that cannabis helps in pain, that's already common knowledge. In the end, what's missing is a standardized product, if people have been using cannabis in the past 5 years, then you would not know where cannabis comes from, is it Cannabis sativa, the European-based form, it's this Indian form that causes more intoxication, there is no standardized medicine for it, there are no standardized extracts for migraine and it was the task that we want to develop quality-assured cannabis extract, where then it is sure that it will not only work today or tomorrow but also over the next 10 years.
The European research team wants to find out which cannabis plant is particularly suitable as a medicinal plant and how to fortify the analgesic substances in this plant. If the project produces an effective remedy for rheumatism and migraine, a profitable market is open. That is not the only reason biochemist Prof. Lienhardt Schmitz from the University of Bern is highly motivated:
In both diseases, in migraine and in rheumatoid arthritis, inflammatory processes are relevant and in the foreground, and in the laboratory in Berne we can molecularly examine these inflammatory processes and measure the effects of hemp extracts or even isolated components on these inflammatory processes. The hope is to inhibit the inflammatory processes with these hemp extracts.
It will be two to three years before scientists can present a tablet suitable for clinical trials. It is already clear: Even a new cannabis product will not be a panacea.
Even if the hemp pill only mild side effects are to be feared – drowsiness, dizziness or blurred vision, as evidenced by the recent American study with 36 subjects – that is for the Elzach migraine doctor Dr. med. Rainer Ihling Reason enough to be skeptical:
In my experience, the natural remedies v.a. in the field of prophylaxis, i. as a prevention of migraine attacks and then usually only if they are attacks that are not strong. If you were to use cannabis now, I would fear that the side effects such as dizziness, mental changes, dizziness, and I do not know any migraine sufferer who would like that. If you use it as an acute remedy, then I can not imagine that the cannabis works there, simply because the substance does not work so fast.